BDBM50110703 6,6-Dimethyl-3-methylsulfanyl-1-(1H-pyrazol-3-yl)-6,7-dihydro-5H-benzo[c]thiophen-4-one::CHEMBL17354

SMILES CSc1sc(-c2cc[nH]n2)c2CC(C)(C)CC(=O)c12

InChI Key InChIKey=YMIKAQYPFQWUEM-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50110703   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50110703(6,6-Dimethyl-3-methylsulfanyl-1-(1H-pyrazol-3-yl)-...)
Affinity DataKi:  234nMAssay Description:Inhibition of human recombinant LRRK2 G2019S mutant using fluorescein- ERM as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50110703(6,6-Dimethyl-3-methylsulfanyl-1-(1H-pyrazol-3-yl)-...)
Affinity DataKi:  377nMAssay Description:Inhibition of GST-tagged human recombinant wild type LRRK2 using fluorescein- ERM as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed